Well, I have been saying for years that I believe the root cause behind Cohens extreme food allergies was that I was given high doses of antibiotics just prior to his birth and directly after. So Im not at all surprised that asthmatics can also be linked to antibiotics as per this article...
" (Reuters Health) - Children whose mothers took antibiotics while they were
pregnant were slightly more likely than other kids to develop asthma in a new
Danish study.
The results don't prove that antibiotics
caused the higher asthma risk, but they support a current theory that the body's
own "friendly" bacteria have a role in whether a child develops asthma, and
antibiotics can disrupt those beneficial bugs.
"We speculate that mothers' use of
antibiotics changes the balance of natural
bacteria, which is transmitted to the newborn, and that such unbalanced bacteria
in early life impact on the immune maturation in the newborn," said Dr. Hans
Bisgaard, one of the authors of the study and a professor at the University of
Copenhagen.
Those effects on the immune system could
lead to asthma later on, although it's still not clear how, said Anita
Kozyrskyj, a professor at the University of Alberta who also studies the
antibiotics-asthma link but wasn't involved in the new study.
Previous research has linked antibiotics
taken during infancy to a higher risk of asthma, although some researchers have
disputed those findings (see Reuters Health stories of May 17, 2011 and February
3, 2011).
To look for effects starting at an even
earlier point in a baby's development, Bisgaard and his colleagues gathered
information from a Danish national birth database of more than 30,000 children
born between 1997 and 2003 and followed for five years.
They found that about 7,300 of the
children, or nearly one quarter, were exposed to antibiotics while their mothers
were pregnant. Among them, just over three percent (238 kids) were hospitalized
for asthma by age five.
In comparison, about 2.5 percent, or 581
of some 23,000 kids whose mothers didn't take antibiotics were hospitalized for
asthma.
After taking into account other
asthma risk factors, Bisgaard's team calculated that the children who had been
exposed to antibiotics were 17 percent more likely to be hospitalized for
asthma.
Similarly, these children were also 18
percent more likely to have been given a prescription for an asthma medication
than kids whose mothers did not take antibiotics when they were pregnant,
according to findings published in The Journal of Pediatrics.
In an email to Reuters Health, Bisgaard
said he expected to see a higher risk of asthma "because the mother is a prime
source of early bacterial colonization of the child, and antibiotics may (have)
disturbed her normal bacterial flora."
Bisgaard's team also looked at a smaller
group of 411 kids who were at higher risk for asthma because their mothers had
the condition and found these children were twice as likely as their peers to
develop asthma too if their mothers took antibiotics during the third trimester
of pregnancy.
Kozyrskyj, who is research chair of the
Women and Children's Health Research Institute, said it's also possible that
something other than the antibiotics are to blame for the findings in both
groups of children - such as the illness that caused the mothers to take
antibiotics.
"This study, it doesn't tell us whether
it's the antibiotic use or whether it's the infection. That's one thing we can't
decipher," she told Reuters Health.
The results don't suggest that women
should avoid taking antibiotics to try to reduce their kids' risk of asthma,
Kozyrskyj emphasized.
Some infections can be quite dangerous to
a fetus, and "there are very good indications for these antibiotics," she
added.
Bisgaard agreed that women should be
treated, "but we see 1/3 of pregnant women in our region receiving treatments
(often for urinary tract infections), which may reflect an uncritical use," he
wrote in an email.
Bisgaard said his group is also studying
the types of bacteria in pregnant mothers and newborn children to get a better
understanding of their role in asthma.
Kozyrskyj said Bisgaard's study suggests
that the development of asthma might start before birth, something researchers
hadn't studied very closely.
"We're beginning to appreciate that some
of the origins of asthma and changes to the immune system, maybe they start
earlier than right after birth. It might be happening in utero," she
said."
SOURCE:
bit.ly/W9SnlJ The Journal of
Pediatrics, online November 8, 2012.
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